|本期目录/Table of Contents|

基于多通道电刺激的食管起搏系统研究(PDF)

《纳米技术与精密工程》[ISSN:1672-6030/CN:12-1351/O3]

期数:
2017年1期
页码:
31-35
栏目:
精密测量
出版日期:
2017-01-15

文章信息/Info

Title:
Research on Esophagus Pacing System Based on Multi-Channel Electrical Stimulation
作者:
许小璇1 陈晓冬1 王邦茂2 张莉莉2 姜雪1 汪毅1 郁道银1
1. 天津大学精密仪器与光电子工程学院,光电信息技术教育部重点实验室,天津 300072; 2. 天津市医科大学总医院消化科,天津 300052
Author(s):
Xu Xiaoxuan1 Chen Xiaodong1 Wang Bangmao2 Zhang Lili2 Jiang Xue1 Wang Yi1 Yu Daoyin1
1. Key Laboratory on OptoElectronics Information Technology of the Ministry of Education, School of Precision Instrument and Opto-Electronics Engineering, Tianjin University, Tianjin 300072, China; 2. Department of Gastroenterology, General Hospital of Tianjin Medical University, Tianjin 300052, China
关键词:
功能性电刺激 多通道 食管起搏 贲门失弛缓症
Keywords:
functional electrical stimulation multi-channel esophagus pacing achalasia
分类号:
R318.14;R571
DOI:
10.13494/j.npe.20150147
文献标识码:
A
摘要:
针对研究功能性电刺激治疗贲门失弛缓症的需求,设计了一种基于多通道电刺激的食管起搏系统.系统以低功耗单片机MSP430为核心处理器,通过对前端脉冲发生信号的处理,控制低功率压控精密恒流电路,采用软件精确延时等技术实现了刺激脉冲的生成、多通道顺序输出、脉冲参数可调等功能.组织5名受试者参加了吞咽信号采集与处理实验.结果显示,系统可以100%检测到受试者吞咽引起的电压变化.将经采集处理后的电压变化值作为比较电路的阈值参数,进一步生成有效的脉冲发生信号.并且利用高精度示波器和万用表对系统生成的刺激脉冲的强度、频率、脉宽3种性能指标进行测试,对所有数据进行误差计算和分析.数据表明,实际测量值与理论值相对误差均小于2.5%,验证了设计原理的正确性和系统的可行性.
Abstract:
To meet the demand of research on functional electrical stimulation in treatment of achalasia, an esophagus pacing system based on multichannel electrical stimulation was designed, with low power MSP430 as the core processor. Functions of stimulation pulses generation, multichannel output and adjustment of pulses parameters were implemented through processing the frontend pulse generating signal and controlling the low power precision voltage controlled current circuit with software precision delay technology. Five volunteers attended the swallowing signal acquisition and processing experiment. The results indicate that 100% voltage variation value caused by the volunteers could be detected and set as the threshold parameter of comparator circuit to generate effective pulse generating signal. The highprecision oscilloscope and the multimeter were used to test the amplitude, frequency and width of stimulation pulses, and the error calculation and analysis of data were carried out. The data indicate that all of the relative errors between measured values and theoretical values were less than 2.5%, which verified the validity of the design theory and the reasonability of the designed system.

参考文献/References

备注/Memo

备注/Memo:
收稿日期: 2016-05-20. 基金项目: 国家自然科学基金资助项目(81370492). 作者简介: 许小璇(1991—),女,硕士研究生. 通讯作者: 陈晓冬,教授,xdchen@tju.edu.cn.
更新日期/Last Update: 2017-02-28