|本期目录/Table of Contents|

Nanopores Fabricated by Glass Capillaries for Biosensing(PDF)

《纳米技术与精密工程》[ISSN:1672-6030/CN:12-1351/O3]

期数:
2013年1期
页码:
9
栏目:
纳米技术
出版日期:
2013-01-15

文章信息/Info

Title:
 基于玻璃毛细管制备用于生物检测的纳米孔
作者:
 Zhang Lei1 Sha Jingjie12 Liu Lei12 Chen Yunfei12
 1. School of Mechanical Engineering, Southeast University, Nanjing 210096, China; 2. Jiangsu Key Laboratory for
Design and Manufacture of Micro-Nano Biomedical Instruments, Southeast University, Nanjing 210096, China
Author(s):
 张磊1 沙菁□12 刘磊12 陈云飞12
 1. 东南大学机械工程学院,南京210096;
2. 江苏省微纳生物医疗器械设计与制造重点实验室,南京210096
关键词:
 nanopores glass capillaries biosensing ion current
Keywords:
 纳米孔 玻璃毛细管 生物检测 离子电流
分类号:
-
DOI:
-
文献标识码:
A
摘要:
 A novel method of fabricating nanopores for biosensing is demonstrated. Experiment shows
that the glass capillaries sealed with paraffin can be stretched to form a nanopore with the diameter of
down to 50 nm. And the key step is to control the thickness of paraffin layer attached to the inner wall,
which can affect the diameter of the nanopore. Bio-molecules were successfully detected in our
experiment, which proves that the glass nanopores fabricated by this method are suitable for biosensing.
Glass nanopores can be fabricated quickly and cheaply by this method, which will be a highly probable
alternative to solid-state nanopores made by silicon nanotechnology.
Abstract:
利用玻璃毛细管,发明了一种新型用于生物检测纳米孔的制备方法. 实验表明,在玻璃毛细管内壁包埋石蜡
层,通过加热玻璃微管的局部,可以拉制形成直径约50 nm的纳米孔. 研究表明,制备玻璃纳米孔的关键步骤是控制
吸附在内壁上的石蜡层的厚度,这直接影响纳米孔的直径. 利用制备的纳米孔,我们已经成功地在实验中检测出生
物分子,表明此种方法制作的玻璃纳米孔可以进行生物检测. 通过这种方法可快速廉价地制作玻璃纳米孔,提供了
一种替代硅技术制作纳米孔的技术.

参考文献/References

备注/Memo

备注/Memo:
更新日期/Last Update: 2013-02-22